Primary Neoplasm in a Vesical Diverticulum: A Case Report / 대한비뇨기과학회지

Primary neoplasms arising in vesical diverticula are rare and present special problems in diagnosis and treatment. We report a case of primary carcinoma arising in vesical diverticula with associated benign prostatic hypertrophy.

Prophylactic Intravesical Chemotherapy in Superficial Bladder Tumors / 대한비뇨기과학회지

Superficial bladder tumors are usually treated by TUR. However, recurrence of the tumor after complete resection occurs in about 50-70%, of the patients with a significant percentage of these recurrences showing a higher degree of malignancy. In 10% of the cases, the tumor progresses to invasive carcinoma. Most of these recurrent tumors will occur within 6-12 months. The multifocal nature of these tumors and the frequent recurrences after TUR indicate a need for adjuvant chemotherapy to reduce or delay the incidence of recurrence tumors. We studied to evaluate prophylactic effects of topical chemotherapy in 116 cases with superficial bladder tumors admitted to the Department of Urology, Keimyung University School of Medicine during the period from Jenuary, 1971 through July, 1985. All patients were followed up for more than 6 months. Study group consists of 83 cases (Thio-tepa: 39, Adriamycin; 44) treated with topical chemotherapy following TUR during the period from January, 1978 through July, 1985. Control group consists of 33 cases treated by TUR only during the period from January 1971 through December, 1977. Following results were obtained: 1. No. of patients with recurrence; In study group, 36Pr In control group. 67% 2. Average interval of recurrence: In study group, 38 months. In control group, 30 months 3. Recurrence rate; In study group, 2.58 In control group, 3.16 4. Complication: local side effects; In TUR + Thio-tepa, 20.5% In TUR + Adriamycin, 15.9%.

A Case of Systemic Chemetherapy in Advanced Seminoma / 대한비뇨기과학회지

Seminoma is one of the most radiosensitive solid tumors. However, the survival of patients with clinically advanced stages B3 and C disease is poor. Most of the failures of treatment in advanced stage seminoma, however, come from systemic diseases outside radiation fields or are secondary to unrecognized non-seminomatous elements. Therefore adjuvant systemic chemotherapy is essential for proper treatment of three patients. Recently we experienced a case of advanced stage seminoma treated with radical inguinal orchiectomy followed by systemic chemotherapy with good result.

Clinical Experience of Metastatic Prostatic Carcinoma / 대한비뇨기과학회지

26 cases of stage D prostatic carcinoma admitted to Dept. of Urology during the period from August 1, 1970 through July 31, 1984 were observed clinically. 1. 26 cases (43.3%) among 60 cases of prostatic carcinoma belonged to stage D at the time of diagnosis. 2. The presenting symptoms showed prostatic obstruction in 21 cases, gross hematuria in 8 cases and lumbago in 2 cases. 3. Serum acid phosphatase activity was elevated in 12 cases (46.2%). Serum alkaline phosphatase activity was elevated in 8 cases (30.8%), 6 cases of whom had osseous metastases. 4. 25 cases revealed adenocarcinoma of the prostate and 1 case revealed squamous cell carcinoma. On the pathological examination, 13 cases were poorly differentiated, 9 cases were intermediate range and 2 cases were well differentiated adenocarcinoma. 5. Orchiectomy was done in 23 cases immediately following biopsy and D. E. S. therapy was done in 7 cases with radiation therapy in 1 case. 6. 15 cases were followed up for more than 1 year, revealing survival rates 73.3% in 1 year, 66.7 % in 2 years and 60% in 3 years.

Renal Cell Carcinoma: Review of 28 Cases / 대한비뇨기과학회지

Review of renal cell carcinoma was made on 28 cases admitted to Dept. of Urology during the period of 11 years from September 1, 1972 through September 30, 1983. 1. There were 17 males and females (ratio of 1.5:1) ranged in age from 19 to 69 years with peak incidence in the 6th decade. 2. The most common symptom and sign was hematuria in 75% but the classic triad of this tumor was present in 29%. 3. The abnormal laboratory findings were elevated ESR in 75%, anemia in 64%, and reversed A/G ratio without hepatic metastasis in 14%. 4. On the urogram renal mass was found in 50%, calyceal destruction in 48%, and nonvisualization of kidney in 39%. 5. The renal angiogram of 10 cases demonstrate hypervascularity in 7 cases, hypovascularity in 1 case, and tumor staining in 7 cases. 6. Staging of the tumor revealed stage in 13 cases, stage III in 5 cases, and stage IV in 7 cases. 7. The histological type revealed clear cell in 20 cases, granular cell in 1 case, and mixed cell in 7 cases. 8. Treatments were simple nephrectomy in 16 cases, simple nephrectomy with adjuvant therapy in 3 cases, and radical nephrectomy with adjuvant therapy in 5 cases.

Complications of Ureteroileal Conduit: Review of 88 Cases / 대한비뇨기과학회지

Review of complications was made on 88 cases of the ileal conduit admitted to Dept. of Urology during the period of 13 years from August 1, 1970 through March 31, 1982. 1. There were 70 males and 18 females (ratio of 4:1) ranged in age from 7 to 72 years with peak incidence in the 6th decade. 2. The most common indication of this procedure was bladder tumor and other indication were renal tuberculosis with contracted bladder, neurogenic bladder, urethral rupture and urethral tumor. 3. 64% of patients with abnormal renal function preoperatively had some improvement postoperatively. 4. Operative mortality was 6.8%. The late mortality was 28%. The operative death rate in benign disease was 6.9% and the late death rate was 3.6%. The operative death rate in malignant disease was 6.9% and the late death rate was 42%. 5. Early complication rate in the benign disease was 17.2% and the late complication was 28.8%. Early complications included wound infection and dehiscence. diarrhea, prolonged ileus. and parastromal dermatitis. The late complications included intestinal obstruction, parastromal dermatitis, stromal stenosis and pyocystis.

A Case of Rhabdomyosarcoma of Spermatic Cord / 대한비뇨기과학회지

Spermatic cord rhabdomyosarcoma is extremely rare and highly malignant. Most of these tumors occur during the first two decades of life. Since 1849, when Rokitansky first described this tumor, 54 cases have been reported in the literature. Herein we add a case of spermatic cord rhabdomyosarcoma in 48 years old man.